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A novel, cell-specific attenuation of a herpes simplex virus type 1 infection in vivo

We have observed a cell-specific attenuation of herpes simplex virus type 1 strain 17syn+ in vivo that was dependent upon the cell type used to grow the virus. Direct corneal infection of rabbits with 17syn+ propagated in Vero cells caused 60% (6 of 10) to develop severe central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Kienzle, Thomas E., Chen, Tsuey-Ming, Mrak, Robert E., Stroop, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086675/
https://www.ncbi.nlm.nih.gov/pubmed/11355305
http://dx.doi.org/10.1007/s004010000281