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Losartan and enalapril decrease viral absorption and interleukin 1 beta production by macrophages in an experimental dengue virus infection

The role of angiotensin II (Ang II) in dengue virus infection remains unknown. The aim of this study was to determine the effect of losartan, an antagonist of the angiotensin II type 1 receptor (AT1 receptor), and enalapril, an inhibitor of angiotensin I-converting enzyme (ACE), on viral antigen exp...

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Detalles Bibliográficos
Autores principales: Hernández-Fonseca, Juan Pablo, Durán, Anyelo, Valero, Nereida, Mosquera, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086732/
https://www.ncbi.nlm.nih.gov/pubmed/26321474
http://dx.doi.org/10.1007/s00705-015-2581-1