Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates

The severe acute respiratory syndrome coronavirus (SARS-CoV) RNA genome is replicated by a virus-encoded RNA replicase, the key component of which is the nonstructural protein 12 (nsp12). In this report, we describe the biochemical properties of a full-length recombinant SARS-CoV nsp12 RNA-dependent...

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Detalles Bibliográficos
Autores principales: Ahn, Dae-Gyun, Choi, Jin-Kyu, Taylor, Deborah R., Oh, Jong-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086750/
https://www.ncbi.nlm.nih.gov/pubmed/22791111
http://dx.doi.org/10.1007/s00705-012-1404-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086750/
https://www.ncbi.nlm.nih.gov/pubmed/22791111
http://dx.doi.org/10.1007/s00705-012-1404-x

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