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Targeted inhibition of immunodeficiency virus replication in lymphocytes through retroviral mediated gene transfer
To test the feasibility of gene therapy for AIDS patients, an animal model is needed to evaluate the efficacy and safety of this approach. Antiviral genes (encoding antisense RNA or viral protein) derived from Simian immunodeficiency virus (SIV) were efficiently targeted into CD4+ lymphocytes throug...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086800/ https://www.ncbi.nlm.nih.gov/pubmed/7504917 http://dx.doi.org/10.1007/BF01313779 |