Neurovirulence in mice of soluble receptor-resistant (srr) mutants of mouse hepatitis virus: intensive apoptosis caused by less virulent srr mutant

 Three soluble receptor-resistant (srr) mutants, srr7, srr11 and srr18, derived from a highly neurotropic mouse hepatitis virus (MHV) JHMV have a single amino acid mutation in the spike (S) protein. We examined using ICR mice whether the amino acids mutated in the mutants were involved in the neurov...

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Detalles Bibliográficos
Autores principales: Matsuyama, S., Watanabe, R., Taguchi, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086838/
https://www.ncbi.nlm.nih.gov/pubmed/11699952
http://dx.doi.org/10.1007/s007050170053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086838/
https://www.ncbi.nlm.nih.gov/pubmed/11699952
http://dx.doi.org/10.1007/s007050170053

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