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Neurovirulence in mice of soluble receptor-resistant (srr) mutants of mouse hepatitis virus: intensive apoptosis caused by less virulent srr mutant

Three soluble receptor-resistant (srr) mutants, srr7, srr11 and srr18, derived from a highly neurotropic mouse hepatitis virus (MHV) JHMV have a single amino acid mutation in the spike (S) protein. We examined using ICR mice whether the amino acids mutated in the mutants were involved in the neurov...

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Detalles Bibliográficos
Autores principales:	Matsuyama, S., Watanabe, R., Taguchi, F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086838/ https://www.ncbi.nlm.nih.gov/pubmed/11699952 http://dx.doi.org/10.1007/s007050170053

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