Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-β production by inhibiting IRF3 activation in immortalized porcine alveolar macrophages

Porcine reproductive and respiratory syndrome virus (PRRSV) infection appears to elicit a weak innate immune response suppressing type 1 interferon (IFN) production. Recent studies have revealed that several nonstructural proteins encoded by the PRRSV genome independently antagonize the type 1 IFN s...

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Detalles Bibliográficos
Autores principales: Sagong, Mingeun, Lee, Changhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086947/
https://www.ncbi.nlm.nih.gov/pubmed/21947566
http://dx.doi.org/10.1007/s00705-011-1116-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086947/
https://www.ncbi.nlm.nih.gov/pubmed/21947566
http://dx.doi.org/10.1007/s00705-011-1116-7

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