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Adenoviral-expressed GP(5) of porcine respiratory and reproductive syndrome virus differs in its cellular maturation from the authentic viral protein but maintains known biological functions

 The ORFs 5, 6 and 7, encoding for the three major structural proteins, GP(5), M and N, of the IAF-Klop strain of PRRSV were cloned and expressed in 293 cells using replication-defective human type 5 adenoviral vectors (hAdVs). Although the M protein gene could be cloned into hAdVs and expressed con...

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Detalles Bibliográficos
Autores principales: Gagnon, C. A., Lachapelle, G., Langelier, Y., Massie, B., Dea, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087108/
https://www.ncbi.nlm.nih.gov/pubmed/12721802
http://dx.doi.org/10.1007/s00705-002-0943-y