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Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems

To reveal the putative cellular factors involved in SARS coronavirus replication, the helicase (Hel, nsp13) of SARS coronavirus was used to screen the cDNA library of rat pulmonary epithelial cells using the yeast two-hybrid system. Positively interacting proteins were further tested using a mammali...

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Detalles Bibliográficos
Autores principales: Chen, Jin-Yan, Chen, Wan-Nan, Poon, Kwok-Man Vincent, Zheng, Bo-Jian, Lin, Xu, Wang, Yong-Xiang, Wen, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087151/
https://www.ncbi.nlm.nih.gov/pubmed/19224332
http://dx.doi.org/10.1007/s00705-009-0323-y