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Characterization and immunogenicity of norovirus capsid-derived virus-like particles purified by anion exchange chromatography
Recombinant baculovirus (BV) expression systems are widely applied in the production of viral capsid proteins and virus-like particles (VLPs) for use as immunogens and vaccine candidates. Traditional density gradient purification of VLPs does not enable complete elimination of BV-derived impurities,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087179/ https://www.ncbi.nlm.nih.gov/pubmed/23229011 http://dx.doi.org/10.1007/s00705-012-1565-7 |