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Characterization and immunogenicity of norovirus capsid-derived virus-like particles purified by anion exchange chromatography

Recombinant baculovirus (BV) expression systems are widely applied in the production of viral capsid proteins and virus-like particles (VLPs) for use as immunogens and vaccine candidates. Traditional density gradient purification of VLPs does not enable complete elimination of BV-derived impurities,...

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Detalles Bibliográficos
Autores principales: Huhti, L., Tamminen, K., Vesikari, T., Blazevic, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087179/
https://www.ncbi.nlm.nih.gov/pubmed/23229011
http://dx.doi.org/10.1007/s00705-012-1565-7