Cargando…

Nintedanib Inhibits Wnt3a-Induced Myofibroblast Activation by Suppressing the Src/β-Catenin Pathway

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by epithelial cell damage, myofibroblast activation, and collagen deposition. Multiple studies have documented that the Wnt/β-catenin pathway is aberrantly activated in IPF and plays a vital role in myofibroblast diffe...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaohe, Liu, Xiaowei, Deng, Ruxia, Gao, Shaoyan, Yu, Haiyan, Huang, Kai, Jiang, Qiuyan, Liu, Rui, Li, Xiaoping, Zhang, Liang, Zhou, Honggang, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087487/
https://www.ncbi.nlm.nih.gov/pubmed/32231574
http://dx.doi.org/10.3389/fphar.2020.00310