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Icariin affects cell cycle progression and proliferation of human retinal pigment epithelial cells via enhancing expression of H19

BACKGROUND: Aberrant proliferation of retinal pigment epithelial (RPE) cells under pathologic condition results in the occurrence of proliferative vitreoretinopathy (PVR). Icariin (ICA)-a flavonol glucoside-has been shown to inhibit proliferation of many cell types, but the effect on RPE cells is un...

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Detalles Bibliográficos
Autores principales: Zhang, Yibing, Li, Min, Han, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087489/
https://www.ncbi.nlm.nih.gov/pubmed/32219038
http://dx.doi.org/10.7717/peerj.8830