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Comparative functional genomic analysis of Alzheimer’s affected and naturally aging brains

BACKGROUND: Alzheimer’s disease (AD) is a prevalent progressive neurodegenerative human disease whose cause remains unclear. Numerous initially highly hopeful anti-AD drugs based on the amyloid-β (Aβ) hypothesis of AD have failed recent late-phase tests. Natural aging (AG) is a high-risk factor for...

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Detalles Bibliográficos
Autores principales: Peng, Yi-Shian, Tang, Chia-Wei, Peng, Yi-Yun, Chang, Hung, Chen, Chien-Lung, Guo, Shu-Lin, Wu, Li-Ching, Huang, Min-Chang, Lee, Hoong-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087547/
https://www.ncbi.nlm.nih.gov/pubmed/32219020
http://dx.doi.org/10.7717/peerj.8682