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Structural insights into the effect of isonucleosides on B-DNA duplexes using molecular-dynamics simulations

Some structural insights into the conformations of the isonucleosides containing duplexes have been provided. Unrestrained molecular-dynamics simulations on 18-mer duplexes with isonucleosides incorporated at the 3'-end or in the center of one strand have been carried out with explicit solvent...

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Detalles Bibliográficos
Autores principales: Jin, Hongwei, Zheng, Suxin, Wang, Zhanli, Luo, Cheng, Shen, Jianhua, Jiang, Hualiang, Zhang, Liangren, Zhang, Lihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087579/
https://www.ncbi.nlm.nih.gov/pubmed/16450112
http://dx.doi.org/10.1007/s00894-005-0085-8