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Structural insights into the effect of isonucleosides on B-DNA duplexes using molecular-dynamics simulations
Some structural insights into the conformations of the isonucleosides containing duplexes have been provided. Unrestrained molecular-dynamics simulations on 18-mer duplexes with isonucleosides incorporated at the 3'-end or in the center of one strand have been carried out with explicit solvent...
Autores principales: | Jin, Hongwei, Zheng, Suxin, Wang, Zhanli, Luo, Cheng, Shen, Jianhua, Jiang, Hualiang, Zhang, Liangren, Zhang, Lihe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087579/ https://www.ncbi.nlm.nih.gov/pubmed/16450112 http://dx.doi.org/10.1007/s00894-005-0085-8 |
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