Recent advances in the detection of base modifications using the Nanopore sequencer

DNA and RNA modifications have important functions, including the regulation of gene expression. Existing methods based on short-read sequencing for the detection of modifications show difficulty in determining the modification patterns of single chromosomes or an entire transcript sequence. Further...

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Detalles Bibliográficos
Autores principales: Xu, Liu, Seki, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087776/
https://www.ncbi.nlm.nih.gov/pubmed/31602005
http://dx.doi.org/10.1038/s10038-019-0679-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087776/
https://www.ncbi.nlm.nih.gov/pubmed/31602005
http://dx.doi.org/10.1038/s10038-019-0679-0

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