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Recent advances in the detection of base modifications using the Nanopore sequencer
DNA and RNA modifications have important functions, including the regulation of gene expression. Existing methods based on short-read sequencing for the detection of modifications show difficulty in determining the modification patterns of single chromosomes or an entire transcript sequence. Further...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087776/ https://www.ncbi.nlm.nih.gov/pubmed/31602005 http://dx.doi.org/10.1038/s10038-019-0679-0 |