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Interaction Behavior Between Niclosamide and Pepsin Determined by Spectroscopic and Docking Methods

The interaction between niclosamide (NIC) and pepsin was investigated using multispectroscopic and molecular docking methods. Binding constant, number of binding sites, and thermodynamic parameters at different temperatures were measured. Results of fluorescence quenching and synchronous fluorescenc...

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Detalles Bibliográficos
Autores principales: Guo, Liuqi, Ma, Xiaoli, Yan, Jin, Xu, Kailin, Wang, Qing, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087788/
https://www.ncbi.nlm.nih.gov/pubmed/26410777
http://dx.doi.org/10.1007/s10895-015-1655-5