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Mx genes: host determinants controlling influenza virus infection and trans-species transmission
The human MxA protein, encoded by the interferon-inducible MX1 gene, is an intracellular influenza A virus (IAV) restriction factor. It can protect transgenic mice from severe IAV-induced disease, indicating a key role of human MxA for host survival and suggesting that natural variations in MX1 may...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087808/ https://www.ncbi.nlm.nih.gov/pubmed/31773252 http://dx.doi.org/10.1007/s00439-019-02092-8 |