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Aldosterone-induced kidney injury is mediated by NFκB activation

BACKGROUND: Aldosterone induces inflammation and fibrosis in the kidney, while nuclear factor κB (NFκB) plays key roles in inflammation mediated by various cytokines. Here, we determined the roles of NFκB activation in aldosterone-induced kidney injury. METHODS: We used unilaterally nephrectomized r...

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Detalles Bibliográficos
Autores principales: Fukuda, Seiichi, Horimai, Chihiro, Harada, Kaori, Wakamatsu, Toshifumi, Fukasawa, Hiroshi, Muto, Susumu, Itai, Akiko, Hayashi, Matsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087855/
https://www.ncbi.nlm.nih.gov/pubmed/21072674
http://dx.doi.org/10.1007/s10157-010-0373-1