MG132-mediated inhibition of the ubiquitin–proteasome pathway ameliorates cancer cachexia

PURPOSE: To evaluate the effect of proteasome inhibitor MG132 in cancer cachexia and to delineate the molecular mechanism underlying. METHODS: We established an experimental cancer cachexia model by subcutaneously implanting colon 26 cells into the armpits of BALB/c mice. Following administration of...

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Detalles Bibliográficos
Autores principales: Zhang, Liuping, Tang, Hua, Kou, Yao, Li, Rui, Zheng, Yueyong, Wang, Qiang, Zhou, Xiaoyu, Jin, Liangbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087863/
https://www.ncbi.nlm.nih.gov/pubmed/23535871
http://dx.doi.org/10.1007/s00432-013-1412-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087863/
https://www.ncbi.nlm.nih.gov/pubmed/23535871
http://dx.doi.org/10.1007/s00432-013-1412-6

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