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MG132-mediated inhibition of the ubiquitin–proteasome pathway ameliorates cancer cachexia
PURPOSE: To evaluate the effect of proteasome inhibitor MG132 in cancer cachexia and to delineate the molecular mechanism underlying. METHODS: We established an experimental cancer cachexia model by subcutaneously implanting colon 26 cells into the armpits of BALB/c mice. Following administration of...
Autores principales: | Zhang, Liuping, Tang, Hua, Kou, Yao, Li, Rui, Zheng, Yueyong, Wang, Qiang, Zhou, Xiaoyu, Jin, Liangbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087863/ https://www.ncbi.nlm.nih.gov/pubmed/23535871 http://dx.doi.org/10.1007/s00432-013-1412-6 |
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