Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies

DNA methyltransferase 1 (DNMT1) is an emerging target for the treatment of cancer, brain disorders, and other diseases. Currently, there are only a few DNMT1 inhibitors with potential application as therapeutic agents or research tools. 5,5-Methylenedisalicylic acid is a novel scaffold previously id...

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Detalles Bibliográficos
Autores principales: Yoo, Jakyung, Medina-Franco, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087970/
https://www.ncbi.nlm.nih.gov/pubmed/21805123
http://dx.doi.org/10.1007/s00894-011-1191-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087970/
https://www.ncbi.nlm.nih.gov/pubmed/21805123
http://dx.doi.org/10.1007/s00894-011-1191-4

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