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Mechanism of Preferential Packaging of Negative Sense Genomic RNA by Viral Nucleoproteins in Crimean-Congo Hemorrhagic Fever Virus

The Crimean-Congo Hemorrhagic Fever (CCHF) is an infectious disease of high virulence and mortality caused by a negative sense RNA nairovirus. The genomic RNA of CCHFV is enwrapped by its nucleoprotein. Positively charged residues on CCHFV nucleoprotein provide multiple binding sites to facilitate g...

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Detalles Bibliográficos
Autores principales: Dayer, Mohammad Reza, Dayer, Mohammad Saaid, Rezatofighi, Seyedeh Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087998/
https://www.ncbi.nlm.nih.gov/pubmed/25632888
http://dx.doi.org/10.1007/s10930-015-9601-6