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Cleavage mechanism of the H5N1 hemagglutinin by trypsin and furin
The cleavage property of hemagglutinin (HA) by different proteases was the prime determinant for influenza A virus pathogenicity. In order to understand the cleavage mechanism, molecular modeling tools were utilized to study the coupled model systems of the proteases, i.e., trypsin and furin and pep...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088033/ https://www.ncbi.nlm.nih.gov/pubmed/18235997 http://dx.doi.org/10.1007/s00726-007-0611-3 |