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Estimating residue evolutionary conservation by introducing von Neumann entropy and a novel gap-treating approach
Evolutionary conservation derived from a multiple sequence alignment is a powerful indicator of the functional significance of a residue, and it can help to predict active sites, ligand-binding sites, and protein interaction interfaces. The results of the existing algorithms in identifying the resid...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088136/ https://www.ncbi.nlm.nih.gov/pubmed/17710364 http://dx.doi.org/10.1007/s00726-007-0586-0 |