Degradation of Lung Protective Angiotensin Converting Enzyme-2 by Meconium in Human Alveolar Epithelial Cells: A Potential Pathogenic Mechanism in Meconium Aspiration Syndrome

BACKGROUND: Pancreatic digestive enzymes present in meconium might be responsible for meconium-induced lung injury. The local Renin Angiotensin System plays an important role in lung injury and inflammation. Particularly, angiotensin converting enzyme-2 (ACE-2) has been identified as a protective lu...

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Detalles Bibliográficos
Autores principales: Gandhi, Chintan K., Holmes, Romel, Gewolb, Ira H., Uhal, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acute Lung Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088148/
https://www.ncbi.nlm.nih.gov/pubmed/30759273
http://dx.doi.org/10.1007/s00408-019-00201-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088148/
https://www.ncbi.nlm.nih.gov/pubmed/30759273
http://dx.doi.org/10.1007/s00408-019-00201-y

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