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Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases

As key regulators of cell signaling, protein kinases (PKs) are attractive targets for therapeutic intervention in a variety of diseases. Herein, we report for the first time the inhibitory activity of polycyclic peptides, particularly, derivatives of glycopeptide antibiotics teicoplanin and eremomyc...

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Detalles Bibliográficos
Autores principales: Cozza, G., Fortuna, M., Meggio, F., Sarno, S., Kubbutat, M. H. G., Totzke, F., Schaechtele, C., Pinna, L. A., Olsufyeva, E. N., Preobrazhenskaya, M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088347/
https://www.ncbi.nlm.nih.gov/pubmed/30472959
http://dx.doi.org/10.1134/S0006297918100073