Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis

Contrasting results have been reported concerning the association of a splice-site polymorphism (rs10774671) in OAS1 with multiple sclerosis (MS). We analysed two OAS1 regions encompassing alternatively spliced exons. While the region carrying the splice-site variant is neutrally evolving, a signatu...

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Detalles Bibliográficos
Autores principales: Cagliani, Rachele, Fumagalli, Matteo, Guerini, Franca R., Riva, Stefania, Galimberti, Daniela, Comi, Giacomo P., Agliardi, Cristina, Scarpini, Elio, Pozzoli, Uberto, Forni, Diego, Caputo, Domenico, Asselta, Rosanna, Biasin, Mara, Paraboschi, Elvezia M., Bresolin, Nereo, Clerici, Mario, Sironi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088416/
https://www.ncbi.nlm.nih.gov/pubmed/21735172
http://dx.doi.org/10.1007/s00439-011-1053-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088416/
https://www.ncbi.nlm.nih.gov/pubmed/21735172
http://dx.doi.org/10.1007/s00439-011-1053-2

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