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Small G Rac1 is involved in replication cycle of dengue serotype 2 virus in EAhy926 cells via the regulation of actin cytoskeleton

Bleeding is a clinical characteristic of severe dengue and may be due to increased vascular permeability. However, the pathogenesis of severe dengue remains unclear. In this study, we showed that the Rac1-microfilament signal pathway was involved in the process of DENV serotype 2 (DENV2) infection i...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wu, Na, Gao, Na, Yan, Wenli, Sheng, Ziyang, Fan, Dongying, An, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088618/
https://www.ncbi.nlm.nih.gov/pubmed/27056258
http://dx.doi.org/10.1007/s11427-016-5042-5