Expression of anti-tumor recombinant IgG- and IgE-like genes in eukaryotic cells

The tandem of humanized variable VL and VH genes (ScFv fragment 4D5) possessing a high affinity to the HER-2/neu oncogene (the epidermal growth factor receptor expressed in many types of human tumors) was attached through a flexible linker to the second exon of human antibodies of IgG or IgE isotype...

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Detalles Bibliográficos
Autores principales: Polanovsky, O. L., Lukash, S. V., Stremovskiy, O. A., Karpenko, D. V., Deyev, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP MAIK Nauka/Interperiodica 2008
Materias:
Molecular Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088638/
https://www.ncbi.nlm.nih.gov/pubmed/32214756
http://dx.doi.org/10.1134/S1022795408080024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088638/
https://www.ncbi.nlm.nih.gov/pubmed/32214756
http://dx.doi.org/10.1134/S1022795408080024

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