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Expression of anti-tumor recombinant IgG- and IgE-like genes in eukaryotic cells
The tandem of humanized variable VL and VH genes (ScFv fragment 4D5) possessing a high affinity to the HER-2/neu oncogene (the epidermal growth factor receptor expressed in many types of human tumors) was attached through a flexible linker to the second exon of human antibodies of IgG or IgE isotype...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SP MAIK Nauka/Interperiodica
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088638/ https://www.ncbi.nlm.nih.gov/pubmed/32214756 http://dx.doi.org/10.1134/S1022795408080024 |