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Polymorphism of 2′-5′-oligoadenylate synthetase (OAS) genes, associated with predisposition to severe forms of tick-borne encephalitis, in human populations of North Eurasia

2′-5′-oligoadenylate synthetases are a family of interferon-induced enzymes playing an important role in antiviral defense in mammals. In the human genome, three genes encoding functional synthetases (OAS1, OAS2 and OAS3) form a cluster. Previously, we found that particular genotypes and/or alleles...

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Detalles Bibliográficos
Autores principales: Barkhash, A. V., Babenko, V. N., Kobzev, V. F., Romaschenko, A. G., Voevoda, M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP MAIK Nauka/Interperiodica 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088653/
https://www.ncbi.nlm.nih.gov/pubmed/32214471
http://dx.doi.org/10.1134/S002689331006004X