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Studying Human Pathogens in Animal Models: Fine Tuning the Humanized Mouse
Humanized mice are crucial tools for studying human pathogens in systemic situations. An animal model of human coronavirus infectious disease has been generated by gene transfer of the human receptor for virus-cell interaction (aminopeptidase N, APN, CD13) into mice. We showed that in vitro and in v...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kluwer Academic Publishers
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088949/ https://www.ncbi.nlm.nih.gov/pubmed/16315087 http://dx.doi.org/10.1007/s11248-005-1676-y |