Cargando…

Studying Human Pathogens in Animal Models: Fine Tuning the Humanized Mouse

Humanized mice are crucial tools for studying human pathogens in systemic situations. An animal model of human coronavirus infectious disease has been generated by gene transfer of the human receptor for virus-cell interaction (aminopeptidase N, APN, CD13) into mice. We showed that in vitro and in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Lassnig, Caroline, Kolb, Andreas, Strobl, Birgit, Enjuanes, Luis, Müller, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088949/
https://www.ncbi.nlm.nih.gov/pubmed/16315087
http://dx.doi.org/10.1007/s11248-005-1676-y