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Optimization of Codon Usage of Poxvirus Genes allows for Improved Transient Expression in Mammalian Cells

Transient expression of viral genes from certain poxviruses in uninfected mammalian cells can sometimes be unexpectedly inefficient. The reasons for poor expression levels can be due to a number of features of the gene cassette, such as cryptic splice sites, polymerase II termination sequences or mo...

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Detalles Bibliográficos
Autores principales: Barrett, John W., Sun, Yunming, Nazarian, Steven H., Belsito, Tara A., Brunetti, Craig R., McFadden, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089053/
https://www.ncbi.nlm.nih.gov/pubmed/16791414
http://dx.doi.org/10.1007/s11262-005-0035-7