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Antigen-conjugated N-trimethylaminoethylmethacrylate Chitosan Nanoparticles Induce Strong Immune Responses After Nasal Administration

PURPOSE: Antigens were conjugated on the surface of N-trimethylaminoethylmethacrylate chitosan (TMC) nanoparticles to induce systemic and mucosal immune responses after nasal immunization. METHODS: TMC was synthesized by free radical polymerization and blank nanoparticles were prepared by ionic cros...

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Detalles Bibliográficos
Autores principales: Liu, Qingfeng, Zheng, Xiaoyao, Zhang, Chi, Shao, Xiayan, Zhang, Xi, Zhang, Qizhi, Jiang, Xinguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089071/
https://www.ncbi.nlm.nih.gov/pubmed/24970313
http://dx.doi.org/10.1007/s11095-014-1441-0