Cargando…

Controllable inhibition of hepatitis B virus replication by a DR1-targeting short hairpin RNA (shRNA) expressed from a DOX-inducible lentiviral vector

As a highly efficient delivery system, lentiviral vectors (LVs) have become a powerful tool to assess the antiviral efficacy of RNA drugs such as short hairpin RNA (shRNA) and decoys. Furthermore, recent advanced systems allow controlled expression of the effector RNA via coexpression of a tetracycl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Weiwei, Peng, Hongquan, Li, Jiafu, Zhao, Xiping, Zhao, Fei, Hu, Kanghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089079/
https://www.ncbi.nlm.nih.gov/pubmed/23397077
http://dx.doi.org/10.1007/s11262-013-0886-2