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Synthesis, physicochemical and biological properties of oligonucleotides incorporated with amino-isonucleosides
Antisense oligonucleotides (ASONs) and siRNAs have been applied extensively for the regulation of cellular and viral gene expression, and RNAi is currently one of the most promising new approaches for anti-tumor and anti-viral therapy. In order to improve bioactivity properties and physicochemical p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SP Science China Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089117/ https://www.ncbi.nlm.nih.gov/pubmed/32214999 http://dx.doi.org/10.1007/s11426-011-4465-x |