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Establishment of a transgenic mouse model with liver-specific expression of secretory immunoglobulin D
Mutation of mevalonate kinase (MVK) is thought to account for most cases of hyperimmunoglobulinemia D syndrome (HIDS) with recurrent fever. However, its mechanism and the relationship between elevated serum immunoglobulin D (IgD) and the clinical features of HIDS are unclear. In this study, we gener...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science China Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089205/ https://www.ncbi.nlm.nih.gov/pubmed/22527518 http://dx.doi.org/10.1007/s11427-012-4301-3 |