Cargando…

Establishment of a transgenic mouse model with liver-specific expression of secretory immunoglobulin D

Mutation of mevalonate kinase (MVK) is thought to account for most cases of hyperimmunoglobulinemia D syndrome (HIDS) with recurrent fever. However, its mechanism and the relationship between elevated serum immunoglobulin D (IgD) and the clinical features of HIDS are unclear. In this study, we gener...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ping, Wei, ZhiGuo, Yan, BoWen, Huang, Tan, Gou, KeMian, Dai, YunPing, Zheng, Min, Wang, MeiLi, Cheng, XueQian, Wang, XiFeng, Xu, Chen, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089205/
https://www.ncbi.nlm.nih.gov/pubmed/22527518
http://dx.doi.org/10.1007/s11427-012-4301-3