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Molecular simulation study of the binding mechanism of [α-PTi(2)W(10)O(40)](7−) for its promising broad-spectrum inhibitory activity to FluV-A neuraminidase

Polyoxometalate (POM) has promising antiviral activities. It shows broad-spectrum inhibiting ability, high efficiency, and low toxicity. Experimental assays show that titanium containing polyoxotungstates have anti-influenza-virus activity. In this paper, the binding mechanisms of five isomers of di...

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Detalles Bibliográficos
Autores principales: Wang, JianPing, Hu, DongHua, Su, ZhongMin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Science China Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089260/
https://www.ncbi.nlm.nih.gov/pubmed/32214733
http://dx.doi.org/10.1007/s11434-010-3271-8