Cargando…
Exploration of structural and physicochemical requirements and search of virtual hits for aminopeptidase N inhibitors
Aminopeptidase N (APN) inhibitors have been reported to be effective in treating of life threatening diseases including cancer. Validated ligand- and structure-based pharmacophore mapping approaches were combined with Bayesian modeling and recursive partitioning to identify structural and physicoche...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089330/ https://www.ncbi.nlm.nih.gov/pubmed/23341006 http://dx.doi.org/10.1007/s11030-013-9422-5 |