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Expression of a functional mouse-human chimeric anti-CD19 antibody in the milk of transgenic mice

Human B cell lymphomas are suitable targets for immunotherapy. Clinical trials with mouse-human chimeric B cell-specific monoclonal antibodies (mAbs) have already shown promising results. However, limitations for their use in clinical trials can be the lack of sufficient amounts and high production...

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Detalles Bibliográficos
Autores principales: van Kuik-Romeijn, Petra, de Groot, Nanda, Hooijberg, Erik, de Boer, Herman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089348/
https://www.ncbi.nlm.nih.gov/pubmed/10951698
http://dx.doi.org/10.1023/A:1008987403484