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Expression of a functional mouse-human chimeric anti-CD19 antibody in the milk of transgenic mice
Human B cell lymphomas are suitable targets for immunotherapy. Clinical trials with mouse-human chimeric B cell-specific monoclonal antibodies (mAbs) have already shown promising results. However, limitations for their use in clinical trials can be the lack of sufficient amounts and high production...
Autores principales: | van Kuik-Romeijn, Petra, de Groot, Nanda, Hooijberg, Erik, de Boer, Herman A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kluwer Academic Publishers
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089348/ https://www.ncbi.nlm.nih.gov/pubmed/10951698 http://dx.doi.org/10.1023/A:1008987403484 |
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