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Preparation, identification, and clinical application of anti-HBs monoclonal antibody that binds both wild-type and immune escape mutant HBsAgs

Using a standard cellular fusion technique and indirect enzyme-linked immunosorbent assay (ELISA), a hybridoma cell line strain secreting anti-HBs monoclonal antibody (mAb) (defined G6 mAb) was obtained. The cells grew and secreted mAb stably. Antibody titers in the culture supernatant and ascites w...

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Detalles Bibliográficos
Autores principales: Li, Fanghe, Zhang, Chunyan, Liu, Jinghua, Zhang, Xiaoyan, Yan, Bing, Zhang, Bo, Huang, Yongguo, Gong, Jingsong, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Higher Education Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089361/
https://www.ncbi.nlm.nih.gov/pubmed/32214990
http://dx.doi.org/10.1007/s11684-009-0047-0