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NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo

Flaviviruses such as yellow fever, dengue or Zika viruses are responsible for significant human and veterinary diseases worldwide. These viruses contain an RNA genome, prone to mutations, which enhances their potential to emerge as pathogens. Bamaga virus (BgV) is a mosquito-borne flavivirus in the...

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Detalles Bibliográficos
Autores principales: Colmant, Agathe M. G., Bielefeldt-Ohmann, Helle, Vet, Laura J., O’Brien, Caitlin A., Bowen, Richard A., Hartwig, Airn E., Davis, Steven, Piyasena, Thisun B. H., Habarugira, Gervais, Harrison, Jessica J., Hobson-Peters, Jody, Hall, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089401/
https://www.ncbi.nlm.nih.gov/pubmed/32203536
http://dx.doi.org/10.1371/journal.pntd.0008166