Design, synthesis and activity evaluation of mannose-based DC-SIGN antagonists

In this article, we describe the design, synthesis and activity evaluation of glycomimetic DC-SIGN antagonists, that use a mannose residue to anchor to the protein carbohydrate recognition domain (CRD). The molecules were designed from the structure of the known pseudo-mannobioside antagonist 1, by...

Descripción completa

Detalles Bibliográficos
Autores principales: Obermajer, Nataša, Sattin, Sara, Colombo, Cinzia, Bruno, Michela, Švajger, Urban, Anderluh, Marko, Bernardi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Full-Length Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089406/
https://www.ncbi.nlm.nih.gov/pubmed/21076980
http://dx.doi.org/10.1007/s11030-010-9285-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089406/
https://www.ncbi.nlm.nih.gov/pubmed/21076980
http://dx.doi.org/10.1007/s11030-010-9285-y

Ejemplares similares