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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

BACKGROUND: Circulating lipoprotein lipids cause coronary heart disease (CHD). However, the precise way in which one or more lipoprotein lipid-related entities account for this relationship remains unclear. Using genetic instruments for lipoprotein lipid traits implemented through multivariable Mend...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G., Sanderson, Eleanor, Palmer, Tom M., Ala-Korpela, Mika, Ference, Brian A., Davey Smith, George, Holmes, Michael V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089422/
https://www.ncbi.nlm.nih.gov/pubmed/32203549
http://dx.doi.org/10.1371/journal.pmed.1003062