Differential effect of lacosamide on Na(v)1.7 variants from responsive and non-responsive patients with small fibre neuropathy

Small fibre neuropathy is a common pain disorder, which in many cases fails to respond to treatment with existing medications. Gain-of-function mutations of voltage-gated sodium channel Na(v)1.7 underlie dorsal root ganglion neuronal hyperexcitability and pain in a subset of patients with small fibr...

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Detalles Bibliográficos
Autores principales: Labau, Julie I R, Estacion, Mark, Tanaka, Brian S, de Greef, Bianca T A, Hoeijmakers, Janneke G J, Geerts, Margot, Gerrits, Monique M, Smeets, Hubert J M, Faber, Catharina G, Merkies, Ingemar S J, Lauria, Giuseppe, Dib-Hajj, Sulayman D, Waxman, Stephen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089662/
https://www.ncbi.nlm.nih.gov/pubmed/32011655
http://dx.doi.org/10.1093/brain/awaa016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089662/
https://www.ncbi.nlm.nih.gov/pubmed/32011655
http://dx.doi.org/10.1093/brain/awaa016

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