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Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum

Latrophilin-2 (Lphn2) and latrophilin-3 (Lphn3) are adhesion GPCRs that serve as postsynaptic recognition molecules in CA1 pyramidal neurons of the hippocampus, where they are localized to distinct dendritic domains and are essential for different sets of excitatory synapses. Here, we studied Lphn2...

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Detalles Bibliográficos
Autores principales: Zhang, Roger Shen, Liakath-Ali, Kif, Südhof, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089768/
https://www.ncbi.nlm.nih.gov/pubmed/32202499
http://dx.doi.org/10.7554/eLife.54443